Conformal prediction of HDAC inhibitors

Author:

Norinder U.12,Naveja J.J.345ORCID,López-López E.3ORCID,Mucs D.16,Medina-Franco J.L.3ORCID

Affiliation:

1. Swetox, Karolinska Institutet, Unit of Toxicology Sciences, Södertälje, Sweden

2. Department of Computer and Systems Sciences, Stockholm University, Kista, Sweden

3. Department of Pharmacy, School of Chemistry, Universidad Nacional Autónoma de México, Mexico City, Mexico

4. PECEM, Faculty of Medicine, Universidad Nacional Autónoma de México, Mexico City, Mexico

5. Department of Life Science Informatics, Bonn-Aachen International Center for Information Technology, University of Bonn, Bonn, Germany

6. Unit of Work Environment Toxicology, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden

Funder

National Council of Science and Technology

Publisher

Informa UK Limited

Subject

Drug Discovery,Molecular Medicine,General Medicine,Bioengineering

Reference33 articles.

1. M. Mottamal, S. Zheng, T.L. Huang, and G. Wang, Histone deacetylase inhibitors in clinical studies as templates for new anticancer agents, Molecules 20 (2015), pp. 3898–3941.

2. HDAC as onco target: Reviewing the synthetic approaches with SAR study of their inhibitors

3. Novel Inhibitors of Human Histone Deacetylase (HDAC) Identified by QSAR Modeling of Known Inhibitors, Virtual Screening, and Experimental Validation

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