Safety, pharmacokinetics and pharmacodynamics of a novel γ-aminobutyric acid (GABA) receptor potentiator, HSK3486, in Chinese patients with hepatic impairment
Author:
Affiliation:
1. Phase I Clinical Trial Unit, First Hospital, Jilin University, Jilin, China
2. Haisco Pharmaceutical Group, Sichuan, China
3. Department of Anesthesiology, First Hospital, Jilin University, Jilin, China
Funder
the capital construction funds
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Publisher
Informa UK Limited
Subject
General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/07853890.2022.2129433
Reference26 articles.
1. Oral Delivery of Propofol with Methoxymethylphosphonic Acid as the Delivery Vehicle
2. Mass balance, pharmacokinetics and pharmacodynamics of intravenous HSK3486, a novel anaesthetic, administered to healthy subjects
3. Design, Synthesis, and Evaluation of Novel 2,6-Disubstituted Phenol Derivatives as General Anesthetics
4. Safety, Pharmacokinetics, and Pharmacodynamics of a Single Bolus of the γ-aminobutyric Acid (GABA) Receptor Potentiator HSK3486 in Healthy Chinese Elderly and Non-elderly
5. Safety and efficacy of ciprofol vs propofol for sedation in intensive care unit patients with mechanical ventilation
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