Targeting cullin-RING ligases for cancer treatment: rationales, advances and therapeutic implications
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Clinical Biochemistry,Biomedical Engineering,Bioengineering,Biotechnology
Link
http://link.springer.com/content/pdf/10.1007/s10616-015-9870-0.pdf
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4. Blank JL, Liu XJ, Cosmopoulos K, Bouck DC, Garcia K, Bernard H, Tayber O, Hather G, Liu R, Narayanan U, Milhollen MA, Lightcap ES (2013) Novel DNA damage checkpoints mediating cell death induced by the NEDD8-activating enzyme inhibitor MLN4924. Cancer Res 73:225–234
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1. Targeting cullin neddylation for cancer and fibrotic diseases;Theranostics;2023
2. The NEDD8-activating enzyme inhibition with MLN4924 sensitizes human cancer cells of different origins to apoptosis and necroptosis;Archives of Biochemistry and Biophysics;2020-09
3. Knockdown of Nedd8‑conjugating enzyme UBE2M suppresses the proliferation and induces the apoptosis of intrahepatic cholangiocarcinoma cells;Oncology Reports;2019-09-20
4. The NEDD8-activating enzyme inhibitor MLN4924 sensitizes a TNFR1+ subgroup of multiple myeloma cells for TNF-induced cell death;Cell Death & Disease;2019-08
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