Natural compound library screening to identify berberine as a treatment for rheumatoid arthritis

Author:

Zhang Li,Tan Min,Mao Jing,Zhang Juan,Wang Xiao-Yuan,Zhang Yan,Duo Rui-Xue,Hao Jia-Yao,Shen Hai-LiORCID

Funder

Gansu Administration of Traditional Chinese Medicine

Lanzhou Science and Technology Bureau, science and technology planning project of Lanzhou

Publisher

Springer Science and Business Media LLC

Subject

General Medicine,Rheumatology

Reference33 articles.

1. Bao CX, Chen HX, Mou XJ, Zhu XK, Zhao Q, Wang XG (2018) GZMB gene silencing confers protection against synovial tissue hyperplasia and articular cartilage tissue injury in rheumatoid arthritis through the MAPK signaling pathway. Biomed Pharmacother 103:346–354. https://doi.org/10.1016/j.biopha.2018.04.023

2. Najm A, Masson FM, Preuss P, Georges S, Ory B, Quillard T, Sood S, Goodyear CS, Veale DJ, Fearon U, Le Goff B, Blanchard F (2020) MicroRNA-17-5p reduces inflammation and bone erosions in mice with collagen-induced arthritis and directly targets the JAK/STAT pathway in rheumatoid arthritis fibroblast-like synoviocytes. Arthritis Rheumatol (Hoboken, N.J.) 72(12):2030–2039. https://doi.org/10.1002/art.41441

3. Rao Y, Fang Y, Tan W, Liu D, Pang Y, Wu X, Zhang C, Li G (2020) Delivery of long non-coding rna NEAT1 by peripheral blood monouclear cells-derived exosomes promotes the occurrence of rheumatoid arthritis via the MicroRNA-23a/MDM2/SIRT6 axis. Front Cell Dev Biol 8:551681. https://doi.org/10.3389/fcell.2020.551681

4. Möller B, Villiger PM (2006) Inhibition of IL-1, IL-6, and TNF-alpha in immune-mediated inflammatory diseases. Springer Semin Immunopathol 27(4):391–408. https://doi.org/10.1007/s00281-006-0012-9

5. Cheng X, Huang T, Wang C, Hao S, Shu L, Wang S, Cheng G, Zhang Q, Huang J, Chen C (2022) Natural compound library screening identifies Oroxin A for the treatment of myocardial ischemia/reperfusion injury. Front Pharmacol 13:894899. https://doi.org/10.3389/fphar.2022.894899

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