Interleukin-21, a potential diagnostic and therapeutic target for systemic lupus erythematosus
Author:
Publisher
Springer Science and Business Media LLC
Subject
Immunology,Immunology and Allergy,Rheumatology
Link
http://link.springer.com/content/pdf/10.1007/s00296-013-2860-7.pdf
Reference14 articles.
1. Pan HF, Wu GC, Fan YG, Leng RX, Peng H, Zhou M, Li BZ, Zhu Y, Tao JH, Li XP, Ye DQ (2013) Decreased serum level of IL-21 in new-onset systemic lupus erythematosus patients. Rheumatol Int 33(9):2337–2342. doi: 10.1007/s00296-013-2724-1
2. Li J, Pan HF, Cen H, Tian J, Ma Y, Tao JH, Ye DQ (2011) Interleukin-21 as a potential therapeutic target for systemic lupus erythematosus. Mol Biol Rep 38(6):4077–4081
3. Nguyen V, Luzina I, Rus H, Tegla C, Chen C, Rus V (2012) IL-21 promotes lupus-like disease in chronic graft-versus-host disease through both CD4 T cell- and B cell-intrinsic mechanisms. J Immunol 189(2):1081–1093
4. Bubier JA, Sproule TJ, Foreman O, Spolski R, Shaffer DJ, Morse HC 3rd, Leonard WJ, Roopenian DC (2009) A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice. Proc Natl Acad Sci USA 106(5):1518–1523
5. Herber D, Brown TP, Liang S, Young DA, Collins M, Dunussi-Joannopoulos K (2007) IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R. Fc reduces disease progression. J Immunol 178(6):3822–3830
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