Clinicopathologic characteristics of ALK rearrangements in primary lung adenocarcinoma with identified EGFR and KRAS status

Author:

Wang Jinghui,Dong Yujie,Cai Yiran,Zhou Lijuan,Wu Shafei,Liu Guimei,Su Dan,Li Xi,Qin Na,Nong Jingying,Jia Hongyan,Zhang Quan,Mu Jing,Zeng Xuan,Zhang Haiqing,Zhang Shucai,Zhang Zongde

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,General Medicine

Reference27 articles.

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2. Camidge DR, Theodoro M, Maxson DA, Skokan M, O’Brien T, Lu X, Doebele RC, Baron AE, Varella-Garcia M (2012) Correlations between the percentage of tumor cells showing an anaplastic lymphoma kinase (ALK) gene rearrangement, ALK signal copy number, and response to crizotinib therapy in ALK fluorescence in situ hybridization-positive nonsmall cell lung cancer. Cancer 118(18):4486–4494. doi: 10.1002/cncr.27411

3. Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, Cibulskis K, Sougnez C, Greulich H, Muzny DM, Morgan MB et al (2008) Somatic mutations affect key pathways in lung adenocarcinoma. Nature 455(7216):1069–1075. doi: 10.1038/nature07423

4. Gainor JF, Varghese AM, Ou SH, Kabraji S, Awad MM, Katayama R, Pawlak A, Mino-Kenudson M, Yeap BY, Riely GJ et al (2013) ALK rearrangements are mutually exclusive with mutations in EGFR or KRAS: an analysis of 1,683 patients with non-small cell lung cancer. Clin Cancer Res 19(15):4273–4281. doi: 10.1158/1078-0432.CCR-13-0318

5. Goldstraw P, Crowley J, Chansky K, Giroux DJ, Groome PA, Rami-Porta R, Postmus PE, Rusch V, Sobin L (2007) The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours. J Thorac Oncol 2(8):706–714. doi: 10.1097/JTO.0b013e31812f3c1a

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