Author:
Xu Nie,Xie Kang,Xin Dong,liang Zhonglei,Zeng Yongjun
Abstract
Abstract
Background
Primary cardiac synovial sarcoma is a rare condition with limited treatment options for advanced stages. Surgery and chemotherapy are currently the mainstay treatments; however, survival rates remain low.
Case presentation
A 64-year-old woman presenting with symptoms of chest tightness and shortness of breath was found to have an obstructive right atrial mass, along with pulmonary infarction and metastasis. She was ultimately diagnosed with advanced primary cardiac synovial sarcoma. Following surgery, the patient’s symptoms improved, and she underwent chemotherapy and anti-angiogenic therapy, but unfortunately, her survival time was only 8 months.
Conclusion
This case report aims to enhance clinicians' understanding of the diagnosis and treatment of primary cardiac synovial sarcoma. Enhancing both survival outcomes and quality of life in individuals with primary cardiac synovial sarcoma continues to present a significant challenge.
Publisher
Springer Science and Business Media LLC
Reference16 articles.
1. Bishop JA, Alaggio R, Zhang L, Seethala RR, Antonescu CR (2015) Adamantinoma-like Ewing family tumors of the head and neck: a pitfall in the differential diagnosis of basaloid and myoepithelial carcinomas. Am J Surg Pathol 39(9):1267–1274. https://doi.org/10.1097/pas.0000000000000460
2. Coli A, Cassano A, Novello M, Ranelletti FO, Lauriola L (2019) Primary cardiac synovial sarcoma: A review correlating outcomes with surgery and adjuvant therapy. J Card Surg 34(11):1321–1327. https://doi.org/10.1111/jocs.14214
3. Fisher C, Montgomery E, Healy V (2003) Calponin and h-caldesmon expression in synovial sarcoma;the use of calponin in diagnosis. Histopathology 42(6):588–593. https://doi.org/10.1046/j.1365-2559.2003.01652.x
4. Hannachi Sassi S, Zargouni N, Saadi Dakhlia M, Mrad K, Cammoun M, Ben Romdhane K (2004) Primary synovial sarcoma of the heart. A clinicopathologic study of one case and review of the literature. Pathologica 96(1):29–34
5. Jo VY, Fletcher CD (2014) WHO classification of soft tissue tumours: an update based on the 2013 (4th) edition. Pathology 46(2):95–104. https://doi.org/10.1097/pat.0000000000000050