REG4 is an indicator for KRAS mutant lung adenocarcinoma with TTF-1 low expression
Author:
Funder
Young Scientists Fund
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/s00432-019-02988-y.pdf
Reference31 articles.
1. Arrieta O, Cardona AF, Martín C et al (2015) Updated frequency of EGFR and KRAS mutations in nonsmall-cell lung cancer in Latin America: the Latin-American Consortium for the Investigation of Lung Cancer (CLICaP). J Thorac Oncol. 10(5):838–843
2. Bishnupuri KS, Luo Q, Murmu N, Houchen CW, Anant S, Dieckgraefe BK (2006a) Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas. Gastroenterology 130(1):137–149
3. Bishnupuri KS, Luo Q, Korzenik JR et al (2006b) Dysregulation of Reg gene expression occurs early in gastrointestinal tumorigenesis and regulates anti-apoptotic genes. Cancer Biol Ther 5(12):1714–1720
4. Bishnupuri KS, Sainathan SK, Bishnupuri K et al (2014) REG4-induced mitogenesis involves Akt-GSK3β-β-Catenin-TCF-4 signaling in human colorectal cancer. Mol Carcinog 53(Suppl 1):E169–E180
5. Chitale D, Gong Y, Taylor BS et al (2009) An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors. Oncogene 28(31):2773–2783
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1. KRAS Mutations in Solid Tumors: Characteristics, Current Therapeutic Strategy, and Potential Treatment Exploration;Journal of Clinical Medicine;2023-01-16
2. REG4 promotes the proliferation and anti-apoptosis of cancer;Frontiers in Cell and Developmental Biology;2022-09-12
3. The effects of REG4 expression on chemoresistance of ovarian cancer;Journal of Obstetrics and Gynaecology;2022-08-05
4. PSC subtyping based on TTF ‐1 and p40 expression reveals distinct molecular characteristics and therapeutic strategies;International Journal of Cancer;2022-06-08
5. Reg4 regulates pancreatic regeneration following pancreatitis via modulating the Notch signaling;Journal of Cellular Physiology;2021-04-26
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