The Antifungal Pipeline: Fosmanogepix, Ibrexafungerp, Olorofim, Opelconazole, and Rezafungin

Author:

Hoenigl MartinORCID,Sprute Rosanne,Egger Matthias,Arastehfar Amir,Cornely Oliver A.,Krause Robert,Lass-Flörl Cornelia,Prattes Juergen,Spec Andrej,Thompson George R.,Wiederhold Nathan,Jenks Jeffrey D.

Funder

national institute of allergy and infectious diseases

Medical University of Graz

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical)

Reference211 articles.

1. Cornely OA, Alastruey-Izquierdo A, Arenz D, Chen SCA, Dannaoui E, Hochhegger B, et al. Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium. Lancet Infect Dis. 2019;19(12):e405–e421.

2. Hoenigl M, Salmanton-García J, Walsh TJ, Nucci M, Neoh CF, Jenks JD, et al. Global guideline for the diagnosis and management of rare mould infections: an initiative of the European Confederation of Medical Mycology in cooperation with the International Society for Human and Animal Mycology and the American Society for Microbiology. Lancet Infect Dis. 2021;21(8):e246–e257.

3. Salmanton-GarcÍa J, Koehler P, Kindo A, Falces-Romero I, GarcÍa-RodrÍguez J, RÁČil Z, et al. Needles in a haystack: extremely rare invasive fungal infections reported in FungiScope®—Global Registry for Emerging Fungal Infections. J Infect. 2020;81(5):802–15.

4. Jenks JD, Seidel D, Cornely OA, Chen S, van Hal S, Kauffman C, et al. Voriconazole plus terbinafine combination antifungal therapy for invasive Lomentospora prolificans infections: analysis of 41 patients from the FungiScope® registry 2008-2019. Clin Microbiol Infect. 2020;S1198-743X(20)30037-9.

5. Arastehfar A, de Almeida Júnior JN, Perlin DS, Ilkit M, Boekhout T, Colombo AL. Multidrug-resistant Trichosporon species: underestimated fungal pathogens posing imminent threats in clinical settings. Crit Rev Microbiol. 2021:1–20.

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