Author:
Wang Wei,Yan Yuxiang,Guo Zheng,Hou Haifeng,Garcia Monique,Tan Xuerui,Anto Enoch Odame,Mahara Gehendra,Zheng Yulu,Li Bo,Kang Timothy,Zhong Zhaohua,Wang Youxin,Guo Xiuhua,Golubnitschaja Olga,
Abstract
AbstractFirst two decades of the twenty-first century are characterised by epidemics of non-communicable diseases such as many hundreds of millions of patients diagnosed with cardiovascular diseases and the type 2 diabetes mellitus, breast, lung, liver and prostate malignancies, neurological, sleep, mood and eye disorders, amongst others. Consequent socio-economic burden is tremendous. Unprecedented decrease in age of maladaptive individuals has been reported. The absolute majority of expanding non-communicable disorders carry a chronic character, over a couple of years progressing from reversible suboptimal health conditions to irreversible severe pathologies and cascading collateral complications. The time-frame between onset of SHS and clinical manifestation of associated disorders is the operational area for an application of reliable risk assessment tools and predictive diagnostics followed by the cost-effective targeted prevention and treatments tailored to the person.This article demonstrates advanced strategies in bio/medical sciences and healthcare focused on suboptimal health conditions in the frame-work of Predictive, Preventive and Personalised Medicine (3PM/PPPM). Potential benefits in healthcare systems and for society at large include but are not restricted to an improved life-quality of major populations and socio-economical groups, advanced professionalism of healthcare-givers and sustainable healthcare economy. Amongst others, following medical areas are proposed to strongly benefit from PPPM strategies applied to the identification and treatment of suboptimal health conditions:
Stress overload associated pathologies
Male and female health
Planned pregnancies
Periodontal health
Eye disorders
Inflammatory disorders, wound healing and pain management with associated complications
Metabolic disorders and suboptimal body weight
Cardiovascular pathologies
Cancers
Stroke, particularly of unknown aetiology and in young individuals
Sleep medicine
Sports medicine
Improved individual outcomes under pandemic conditions such as COVID-19.
Funder
Rheinische Friedrich-Wilhelms-Universität Bonn
Publisher
Springer Science and Business Media LLC
Subject
Biochemistry, medical,Health Policy,Drug Discovery
Cited by
74 articles.
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