The concern about noradrenergic and antimuscarinic agents for OSA
Author:
Funder
Natural Science Foundation of Guangdong Province
Publisher
Springer Science and Business Media LLC
Subject
Physiology (medical),Neurology,Neuropsychology and Physiological Psychology,Physiology
Link
https://link.springer.com/content/pdf/10.1007/s41105-021-00367-0.pdf
Reference5 articles.
1. Taranto-Montemurro L, Messineo L, Sands SA, Azarbarzin A, Marques M, Edwards BA, Eckert DJ, White DP, Wellman A. The combination of atomoxetine and oxybutynin greatly reduces obstructive sleep apnea severity. A randomized, placebo-controlled, double-blind crossover trial. Am J Respir Crit Care Med. 2019;199(10):1267–76. https://doi.org/10.1164/rccm.201808-1493OC.
2. Lim R, Messineo L, Grunstein RR, Carberry JC, Eckert DJ. The noradrenergic agent reboxetine plus the antimuscarinic hyoscine butylbromide reduces sleep apnoea severity: a double-blind, placebo-controlled, randomised crossover trial. J Physiol. 2021. https://doi.org/10.1113/JP281912.
3. Aishah A, Lim R, Sands SA, Taranto-Montemurro L, Wellman A, Carberry JC, Eckert DJ. Different antimuscarinics when combined with atomoxetine have differential effects on obstructive sleep apnea severity. J Appl Physiol (1985). 2021;130(5):1373–82. https://doi.org/10.1152/japplphysiol.01074.2020.
4. Tempesta D, Socci V, De Gennaro L, Ferrara M. Sleep and emotional processing. Sleep Med Rev. 2018;40:183–95. https://doi.org/10.1016/j.smrv.2017.12.005.
5. Eckert DJ, Owens RL, Kehlmann GB, Wellman A, Rahangdale S, Yim-Yeh S, White DP, Malhotra A. Eszopiclone increases the respiratory arousal threshold and lowers the apnoea/hypopnoea index in obstructive sleep apnoea patients with a low arousal threshold. Clin Sci (1979). 2011;120(12):505–14. https://doi.org/10.1042/CS20100588.
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