The attenuated hepatic clearance of propionate increases cardiac oxidative stress in propionic acidemia
Author:
Funder
Propionic Acidemia Foundation
National Outstanding Youth Science Fund Project of National Natural Science Foundation of China
National Institute on Alcohol Abuse and Alcoholism
Publisher
Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1007/s00395-024-01066-w.pdf
Reference70 articles.
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2. Alvarez M, Ruiz-Sala P, Perez B, Desviat LR, Richard E (2023) Dysregulated cell homeostasis and miRNAs in human iPSC-derived cardiomyocytes from a propionic acidemia patient with cardiomyopathy. Int J Mol Sci. https://doi.org/10.3390/ijms24032182
3. Amaral AU, Cecatto C, Castilho RF, Wajner M (2016) 2-Methylcitric acid impairs glutamate metabolism and induces permeability transition in brain mitochondria. J Neurochem 137:62–75. https://doi.org/10.1111/jnc.13544
4. Bartolomaeus H, Balogh A, Yakoub M, Homann S, Marko L, Hoges S, Tsvetkov D, Krannich A, Wundersitz S, Avery EG, Haase N, Kraker K, Hering L, Maase M, Kusche-Vihrog K, Grandoch M, Fielitz J, Kempa S, Gollasch M, Zhumadilov Z, Kozhakhmetov S, Kushugulova A, Eckardt KU, Dechend R, Rump LC, Forslund SK, Muller DN, Stegbauer J, Wilck N (2019) Short-chain fatty acid propionate protects from hypertensive cardiovascular damage. Circulation 139:1407–1421. https://doi.org/10.1161/CIRCULATIONAHA.118.036652
5. Baumgartner D, Scholl-Burgi S, Sass JO, Sperl W, Schweigmann U, Stein JI, Karall D (2007) Prolonged QTc intervals and decreased left ventricular contractility in patients with propionic acidemia. J Pediatr 150:192-197.e191. https://doi.org/10.1016/j.jpeds.2006.11.043
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