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ALOX5AP is an Indicator for High CD8 Lymphocyte Infiltration and “Hot” Tumor Microenvironment in Osteosarcoma: A Bioinformatic Study

  • Published:2023-04-11 Issue:6 Volume:61 Page:2363-2381
  • ISSN:0006-2928
  • Container-title:Biochemical Genetics
  • language:en
  • Short-container-title:Biochem Genet

Author:

Chen Yongjun,Zeng Cheng,Zhang Xue,Hua Qiang

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,General Medicine,Ecology, Evolution, Behavior and Systematics,Biochemistry

Reference34 articles.

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2. Behjati S, Tarpey PS, Haase K, Ye H, Young MD, Alexandrov LB, Farndon SJ, Collord G, Wedge DC, Martincorena I, Cooke SL, Davies H, Mifsud W, Lidgren M, Martin S, Latimer C, Maddison M, Butler AP, Teague JW, Pillay N, Shlien A, McDermott U, Futreal PA, Baumhoer D, Zaikova O, Bjerkehagen B, Myklebost O, Amary MF, Tirabosco R, Van Loo P, Stratton MR, Flanagan AM, Campbell PJ (2017) Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma. Nat Commun 8:15936. https://doi.org/10.1038/ncomms15936

3. Cao M, Zhang J, Xu H, Lin Z, Chang H, Wang Y, Huang X, Chen X, Wang H, Song Y (2020) Identification and development of a novel 4-gene immune-related signature to predict osteosarcoma prognosis. Front Mol Biosci 7:608368. https://doi.org/10.3389/fmolb.2020.608368

4. Chen X, Bahrami A, Pappo A, Easton J, Dalton J, Hedlund E, Ellison D, Shurtleff S, Wu G, Wei L, Parker M, Rusch M, Nagahawatte P, Wu J, Mao S, Boggs K, Mulder H, Yergeau D, Lu C, Ding L, Edmonson M, Qu C, Wang J, Li Y, Navid F, Daw NC, Mardis ER, Wilson RK, Downing JR, Zhang J, Dyer MA (2014) Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma. Cell Rep 7(1):104–112. https://doi.org/10.1016/j.celrep.2014.03.003

5. Codreanu SG, Hoeksema MD, Slebos RJC, Zimmerman LJ, Rahman SMJ, Li M, Chen SC, Chen H, Eisenberg R, Liebler DC, Massion PP (2017) Identification of proteomic features to distinguish benign pulmonary nodules from lung adenocarcinoma. J Proteome Res 16(9):3266–3276. https://doi.org/10.1021/acs.jproteome.7b00245

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