Prostaglandin Endoperoxide H Synthase-2 (PGHS-2) Variants and Risk of Obesity and Microvascular Dysfunction Among Tunisians: Relevance of rs5277 (306G/C) and rs5275 (8473T/C) Genetic Markers

Author:

Touir AhlemORCID,Boumiza Soumaya,Nasr Hela ben,Bchir Sarra,Tabka Zouhair,Norel Xavier,Chahed Karim

Funder

Ministère de l’Enseignement Supérieur et de la Recherche Scientifique

Ministry of Public Health

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,General Medicine,Ecology, Evolution, Behavior and Systematics,Biochemistry

Reference63 articles.

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3. Barry EL, Sansbury LB, Grau MV, Ali IU, Tsang S, Munroe DJ, Ahnen DJ, Sandler RS, Saibil F, Gui J, Bresalier RS, McKeown-Eyssen GE, Burke C, Baron JA (2009) Cyclooxygenase-2 polymorphisms, aspirin treatment, and risk for colorectal adenoma recurrence-data from a randomized clinical trial. Cancer Epidemiol Biomark Prev 18(10):2726–2733. https://doi.org/10.1158/1055-9965.EPI-09-0363

4. Ben Nasr H, Chahed K, Bouaouina N, Chouchane L (2009) PTGS2 (COX-2) -765 G>C functional promoter polymorphism and its association with risk and lymph node metastasis in nasopharyngeal carcinoma. Mol Biol Rep 36(1):193–200. https://doi.org/10.1007/s11033-007-9166-3

5. Boumiza S, Bchir S, Ben Nasr H, Abbassi A, Jacob MP, Norel X, Tabka Z, Chahed K (2017) Role of MMP-1 (-519A/G, -1607 1G/2G), MMP-3 (Lys45Glu), MMP-7 (-181A/G), and MMP-12 (-82A/G) variants and plasma MMP levels on obesity-related phenotypes and microvascular reactivity in a Tunisian population. Dis Mark 2017:6198526. https://doi.org/10.1155/2017/6198526

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