Integrated machine learning-based virtual screening and biological evaluation for identification of potential inhibitors against cathepsin K

Author:

Parwez Shahid,Chaurasia Animesh,Mahapatra Pinaki Parsad,Ahmed Shakil,Siddiqi Mohammad Imran

Funder

Department of Biotechnology, Ministry of Science and Technology, India

Publisher

Springer Science and Business Media LLC

Reference34 articles.

1. Aghamohammadzadeh N, Najafipour F, Bahrami AMIR, Niafar MITRA, Baglar L, Hajiegrary H, Aliasgharzadeh A, Mobasseri M (2009) Evaluation of effective factors in decreased bone density in patients with osteoporosis and osteopenia. J Gorgan Univ Med Sci 11(2)

2. Zamani B, Ebadi SAR, Ahmadvand AFSHIN, Mousavi GH (2010) The frequency of osteoporosis in hip fracture following minor trauma and the resulting mortality rate and direct treatment costs in patients over 45 years old in Kashan Naghavi Hospital during 2005–2007. J Kerman Univ Med Sci 17(2):137–144

3. Langdahl BL (2021) Overview of treatment approaches to osteoporosis. Br J Pharmacol 178(9):1891–1906

4. Skjødt MK, Frost M, Abrahamsen B (2019) Side effects of drugs for osteoporosis and metastatic bone disease. Br J Clin Pharmacol 85(6):1063-1071

5. Panwar P, Law S, Jamroz A, Azizi P, Zhang D, Ciufolini M, Brömme D (2018) Tanshinones that selectively block the collagenase activity of cathepsin K provide a novel class of ectosteric antiresorptive agents for bone. Br J Pharmacol 175(6):902–923

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