Construction of IRAK4 inhibitor activity prediction model based on machine learning
Author:
Funder
Science and Technology Plan Project of Guizhou
Publisher
Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1007/s11030-024-10926-5.pdf
Reference46 articles.
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2. Flannery S, Bowie AG (2010) The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling. Biochem Pharmacol 80:1981–1991
3. Chaudhary D, Robinson S, Romero DL (2015) Recent advances in the discovery of small molecule inhibitors of interleukin-1 receptor-associated kinase 4 (IRAK4) as a therapeutic target for inflammation and oncology disorders: Miniperspective. J Med Chem 58:96–110
4. Buckley GM, Gowers L, Higueruelo AP, Jenkins K, Mack SR, Morgan T, Parry DM, Pitt WR, Rausch O, Richard MD (2008) IRAK-4 inhibitors. Part 1: a series of amides. Bioorgan Med Chem Lett 18:3211–3214
5. Coccia M, Harrison OJ, Schiering C, Asquith MJ, Becher B, Powrie F, Maloy KJ (2012) IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+ Th17 cells. J Exp Med 209:1595–1609
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