Novel B, C-ring truncated deguelin derivatives reveals as potential inhibitors of cyclin D1 and cyclin E using molecular docking and molecular dynamic simulation-Reference-Cited by-同舟云学术

Novel B, C-ring truncated deguelin derivatives reveals as potential inhibitors of cyclin D1 and cyclin E using molecular docking and molecular dynamic simulation

Published:2021-10-09 Issue: Volume: Page:
ISSN:1381-1991
Container-title:Molecular Diversity
language:en
Short-container-title:Mol Divers

Author:

Lokhande Kiran Bharat,Ghosh Payel,Nagar Shuchi,Venkateswara Swamy K.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Drug Discovery,Molecular Biology,General Medicine,Information Systems,Catalysis

Link

https://link.springer.com/content/pdf/10.1007/s11030-021-10334-z.pdf

Reference47 articles.

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2. Azevedo-Barbosa H, Ferreira-Silva GÁ, Silva CF, de Souza TB, Dias DF, de Paula A, Ionta M, Carvalho DT (2019) Phenylpropanoid-based sulfonamide promotes cyclin D1 and cyclin E down-regulation and induces cell cycle arrest at G1/S transition in estrogen positive MCF-7 cell line. Toxicol In Vitro: Int J Publ Assoc BIBRA 59:150–160. https://doi.org/10.1016/j.tiv.2019.04.023

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4. Weinstat-Saslow D, Merino MJ, Manrow RE, Lawrence JA, Bluth RF, Wittenbel KD, Simpson JF, Page DL, Steeg PS (1995) Overexpression of cyclin D mRNA distinguishes invasive and in situ breast carcinomas from non-malignant lesions. Nat Med 1(12):1257–1260. https://doi.org/10.1038/nm1295-1257

5. Wang F, Mao A, Tang J, Zhang Q, Yan J, Wang Y, Di C, Gan L, Sun C, Zhang H (2019) microRNA-16-5p enhances radiosensitivity through modulating Cyclin D1/E1-pRb-E2F1 pathway in prostate cancer cells. J Cell Physiol 234(8):13182–13190. https://doi.org/10.1002/jcp.27989

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