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Triple combination of FDA-approved drugs including flufenamic acid, clarithromycin and zanamivir improves survival of severe influenza in mice

  • Published:2018-05-07 Issue:9 Volume:163 Page:2349-2358
  • ISSN:0304-8608
  • Container-title:Archives of Virology
  • language:en
  • Short-container-title:Arch Virol

Author:

Lee Andrew C. Y.,To Kelvin K. W.,Zhang Anna J. X.,Zhu Houshun,Li Can,Zhang Ricky R.,Hung Ivan F. N.,Kao Richard Y. T.,Chan Kwok-Hung,Yuen Kwok-Yung

Funder

Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the Ministry of Education of China

Mr. Larry Chi-Kin Yung

Professor Richard Yu and Mrs. Carol Yu

Providence Foundation Ltd

Cheer Master Investments

Publisher

Springer Science and Business Media LLC

Subject

Virology,General Medicine

Reference40 articles.

1. Cheng VC, To KK, Tse H, Hung IF, Yuen KY (2012) Two years after pandemic influenza A/2009/H1N1: what have we learned? Clin Microbiol Rev 25(2):223–263. https://doi.org/10.1128/CMR.05012-11

2. Alame MM, Massaad E, Zaraket H (2016) Peramivir: a novel intravenous neuraminidase inhibitor for treatment of acute influenza infections. Front Microbiol 7:450. https://doi.org/10.3389/fmicb.2016.00450

3. To KK, Song W, Lau SY, Que TL, Lung DC, Hung IF, Chen H, Yuen KY (2014) Unique reassortant of influenza A(H7N9) virus associated with severe disease emerging in Hong Kong. J Infect 69(1):60–68. https://doi.org/10.1016/j.jinf.2014.02.012

4. Muthuri SG, Venkatesan S, Myles PR, Leonardi-Bee J, Al Khuwaitir TS, Al Mamun A, Anovadiya AP, Azziz-Baumgartner E, Baez C, Bassetti M, Beovic B, Bertisch B, Bonmarin I, Booy R, Borja-Aburto VH, Burgmann H, Cao B, Carratala J, Denholm JT, Dominguez SR, Duarte PA, Dubnov-Raz G, Echavarria M, Fanella S, Gao Z, Gerardin P, Giannella M, Gubbels S, Herberg J, Iglesias AL, Hoger PH, Hu X, Islam QT, Jimenez MF, Kandeel A, Keijzers G, Khalili H, Knight M, Kudo K, Kusznierz G, Kuzman I, Kwan AM, Amine IL, Langenegger E, Lankarani KB, Leo YS, Linko R, Liu P, Madanat F, Mayo-Montero E, McGeer A, Memish Z, Metan G, Mickiene A, Mikic D, Mohn KG, Moradi A, Nymadawa P, Oliva ME, Ozkan M, Parekh D, Paul M, Polack FP, Rath BA, Rodriguez AH, Sarrouf EB, Seale AC, Sertogullarindan B, Siqueira MM, Skret-Magierlo J, Stephan F, Talarek E, Tang JW, To KK, Torres A, Torun SH, Tran D, Uyeki TM, Van Zwol A, Vaudry W, Vidmar T, Yokota RT, Zarogoulidis P, Investigators PC, Nguyen-Van-Tam JS (2014) Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data. Lancet Respir Med 2(5):395–404. https://doi.org/10.1016/S2213-2600(14)70041-4

5. To KK, Hung IF, Li IW, Lee KL, Koo CK, Yan WW, Liu R, Ho KY, Chu KH, Watt CL, Luk WK, Lai KY, Chow FL, Mok T, Buckley T, Chan JF, Wong SS, Zheng B, Chen H, Lau CC, Tse H, Cheng VC, Chan KH, Yuen KY (2010) Delayed clearance of viral load and marked cytokine activation in severe cases of pandemic H1N1 2009 influenza virus infection. Clin Infect Dis 50(6):850–859. https://doi.org/10.1086/650581

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