MicroRNA-34a-5p induces cell cycle arrest and leads to spermatogenesis failure by targeting CDC25A-Reference-Cited by-同舟云学术

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MicroRNA-34a-5p induces cell cycle arrest and leads to spermatogenesis failure by targeting CDC25A

Published:2025-05-26 Issue:1 Volume:82 Page:
ISSN:1420-9071
Container-title:Cellular and Molecular Life Sciences
language:en
Short-container-title:Cell. Mol. Life Sci.

Author:

Lin Meina,Shi Ziyan,Chen Xinren,Ni Xiang,Sui Yu,Li Huan,Guan Changji,Tian Zhiying,Jiang Miao,Jiang Jingyi,Guo Tingchao,Lu Yongping^ORCID

Funder

The young and middle-aged science and technology innovation talents support program of Shenyang

Basic Research Project of the Education Department of Liaoning Province

Shenyang science and technology plan project

The project of supporting the high-quality development of science and technology of China Medical University

Publisher

Springer Science and Business Media LLC

Link

https://link.springer.com/content/pdf/10.1007/s00018-025-05738-1.pdf

Reference41 articles.

1. Hu X, Ding Z, Hong Z, Zou Z, Feng Y, Zhu R, Ma J, Ge X, Li C, Yao B (2018) Spermatogenesis improved by suppressing the high level of endogenous gonadotropins in idiopathic non-obstructive azoospermia: a case control pilot study. Reprod Biol Endocrinol 16(1):91. https://doi.org/10.1186/s12958-018-0401-7

2. Cervan-Martin M, Castilla JA, Palomino-Morales RJ, Carmona FD (2020) Genetic landscape of nonobstructive azoospermia and new perspectives for the clinic. J Clin Med 9(2). https://doi.org/10.3390/jcm9020300

3. Aljubran A, Safar O, Elatreisy A, Alwadai R, Shalkamy O, Assiri HM, Eskander M, Arezki A, Ibrahim A (2022) Factors predicting successful sperm retrieval in men with nonobstructive azoospermia: A single center perspective. Health Sci Rep 5(4):e727. https://doi.org/10.1002/hsr2.727

4. Chen X, Ba Y, Ma L, Cai X, Yin Y, Wang K, Guo J, Zhang Y, Chen J, Guo X et al (2008) Characterization of MicroRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res 18(10):997–1006. https://doi.org/10.1038/cr.2008.282

5. Herrero-Aguayo V, Saez-Martinez P, Jimenez-Vacas JM, Moreno-Montilla MT, Montero-Hidalgo AJ, Perez-Gomez JM, Lopez-Canovas JL, Porcel-Pastrana F, Carrasco-Valiente J, Anglada FJ et al (2022) Dysregulation of the mirnome unveils a crosstalk between obesity and prostate cancer: miR-107 Asa personalized diagnostic and therapeutic tool. Mol Ther Nucleic Acids 27:1164–1178. https://doi.org/10.1016/j.omtn.2022.02.010

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