Erythropoietin Reduces Neurodegeneration and Long-Term Memory Deficits Following Sevoflurane Exposure in Neonatal Rats

Author:

Goyagi ToruORCID

Funder

Grant-in-Aid for Scientific Research (C), JSPS KAKENHI

Publisher

Springer Science and Business Media LLC

Subject

Toxicology,General Neuroscience

Reference39 articles.

1. Acharya NK, Goldwaser EL, Forsberg MM, Godsey GA, Johnson CA, Sarkar A, DeMarshall C, Kosciuk MC, Dash JM, Hale CP, Leonard DM, Appelt DM, Nagele RG (2015) Sevoflurane and isoflurane induce structural changes in brain vascular endothelial cells and increase blood-brain barrier permeability: possible link to postoperative delirium and cognitive decline. Brain Res 1620:29–41. https://doi.org/10.1016/j.brainres.2015.04.054

2. Andropoulos DB, Greene MF (2017) Anesthesia and developing brains—implications of the FDA warning. N Engl J Med 376:905–907

3. Davidson AJ, Disma N, de Graaff JC, Withington DE, Dorris L, Bell G, Stargatt R, Bellinger DC, Schuster T, Arnup SJ, Hardy P, Hunt RW, Takagi MJ, Giribaldi G, Hartmann PL, Salvo I, Morton NS, von Ungern Sternberg B, Locatelli BG, Wilton N, Lynn A, Thomas JJ, Polaner D, Bagshaw O, Szmuk P, Absalom AR, Frawley G, Berde C, Ormond GD, Marmor J, McCann M, GAS consortium (2016) Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial. Lancet 387:239–250. https://doi.org/10.1016/s0140-6736(15)00608-x

4. Digicaylioglu M, Lipton SA (2001) Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-κB signalling cascades. Nature 412:641–647

5. Disma N, Mondardini MC, Terrando N, Absalom AR, Bilotta F (2016) A systematic review of methodology applied during preclinical anesthetic neurotoxicity studies: important issues and lessons relevant to the design of future clinical research. Paediatr Anaesth 26:6–36. https://doi.org/10.1111/pan.12786

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