Effect of the mGlu4 positive allosteric modulator ADX-88178 on parkinsonism, psychosis-like behaviours and dyskinesia in the MPTP-lesioned marmoset
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology
Link
https://link.springer.com/content/pdf/10.1007/s00213-023-06428-1.pdf
Reference43 articles.
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2. Beurrier C, Lopez S, Revy D, Selvam C, Goudet C, Lherondel M, Gubellini P, Kerkerian-LeGoff L, Acher F, Pin JP, Amalric M (2009) Electrophysiological and behavioral evidence that modulation of metabotropic glutamate receptor 4 with a new agonist reverses experimental parkinsonism. FASEB J 23(10):3619–3628. https://doi.org/10.1096/fj.09-131789
3. Chang A, Fox SH (2016) Psychosis in Parkinson’s Disease: Epidemiology, Pathophysiology, and Management. Drugs 76(11):1093–1118. https://doi.org/10.1007/s40265-016-0600-5
4. Charvin D (2018) mGlu4 allosteric modulation for treating Parkinson’s disease. Neuropharmacology 135:308–315. https://doi.org/10.1016/j.neuropharm.2018.03.027
5. Charvin D, Di Paolo T, Bezard E, Gregoire L, Takano A, Duvey G, Pioli E, Halldin C, Medori R, Conquet F (2018) An mGlu4-Positive Allosteric Modulator Alleviates Parkinsonism in Primates. Mov Disord 33(10):1619–1631. https://doi.org/10.1002/mds.27462
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