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Research progress of PPARγ regulation of cholesterol and inflammation in Alzheimer's disease

  • Published:2023-02-01 Issue:3 Volume:38 Page:839-854
  • ISSN:0885-7490
  • Container-title:Metabolic Brain Disease
  • language:en
  • Short-container-title:Metab Brain Dis

Author:

Gu Lili,Ju Yue,Hu Min,Zheng Miao,Li Qin,Zhang XinyueORCID

Funder

Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province

Chinese traditional medicine and Technology project of Zhejiang Province

Natural Science Foundation of Zhejiang province

Medical and Health Science and Technology Project of Zhejiang Province

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Neurology (clinical),Biochemistry

Reference145 articles.

1. Ahn D, Kim J, Nam G, Zhao X, Kwon J, Hwang JY, . . . Chung SJ (2022) Ethyl gallate dual-targeting PTPN6 and PPARγ shows anti-diabetic and anti-obese effects. Int J Mol Sci 23(9). Retrieved from https://mdpi-res.com/d_attachment/ijms/ijms-23-05020/article_deploy/ijms-23-05020-v2.pdf?version=1651736266, https://doi.org/10.3390/ijms23095020

2. Assaf N, El-Shamarka ME, Salem NA, Khadrawy YA, El Sayed NS (2020) Neuroprotective effect of PPAR alpha and gamma agonists in a mouse model of amyloidogenesis through modulation of the Wnt/beta catenin pathway via targeting alpha- and beta-secretases. Prog Neuropsychopharmacol Biol Psychiatry 97:109793. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/31669201, https://doi.org/10.1016/j.pnpbp.2019.109793

3. Bacchetti T, Vignini A, Giulietti A, Nanetti L, Provinciali L, Luzzi S, . . . Ferretti G (2015) Higher levels of oxidized low density lipoproteins in alzheimer's disease patients: roles for platelet activating factor acetyl hydrolase and paraoxonase-1. J Alzheimers Dis 46(1):179–186. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/25720407, https://doi.org/10.3233/JAD-143096

4. Badana AK, Chintala M, Gavara MM, Naik S, Kumari S, Kappala VR, . . . Malla RR (2018) Lipid rafts disruption induces apoptosis by attenuating expression of LRP6 and survivin in triple negative breast cancer. Biomed Pharmacother 97:359–368. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/29091885, https://doi.org/10.1016/j.biopha.2017.10.045

5. Bedir A, Aliyazicioglu Y, Kahraman H, Yurdakul Z, Uysal M, Suvaci DE, . . . Alvur M (2006) Genotoxicity in rats treated with the antidiabetic agent, rosiglitazone. Environ Mol Mutagen 47(9):718–724. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/17078099, https://doi.org/10.1002/em.20261

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