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Development of novel treatments for amyotrophic lateral sclerosis

  • Published:2023-12-11 Issue: Volume: Page:
  • ISSN:0885-7490
  • Container-title:Metabolic Brain Disease
  • language:en
  • Short-container-title:Metab Brain Dis

Author:

Sun ZhuoORCID,Zhang BoORCID,Peng YingORCID

Funder

National Natural Sciences Foundation of China

CAMS Innovation Fund for Medical Sciences

Disciplines construction project

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Neurology (clinical),Biochemistry

Reference87 articles.

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2. Babu S, Hightower BG, Chan J, Zürcher NR, Kivisäkk P, Tseng CJ, Sanders DL, Robichaud A, Banno H, Evora A, Ashokkumar A, Pothier L, Paganoni S, Chew S, Dojillo J, Matsuda K, Gudesblatt M, Berry JD, Cudkowicz ME, Hooker JM, Atassi N (2021) Ibudilast (MN-166) in amyotrophic lateral sclerosis- an open label, safety and pharmacodynamic trial. Neuroimage Clin 30:102672. https://doi.org/10.1016/j.nicl.2021.102672

3. Baughn MW, Melamed Z, López-Erauskin J, Beccari MS, Ling K, Zuberi A, Presa M, Gonzalo-Gil E, Maimon R, Vazquez-Sanchez S, Chaturvedi S, Bravo-Hernández M, Taupin V, Moore S, Artates JW, Acks E, Ndayambaje IS, Agra de Almeida Quadros AR, Jafar-Nejad P, Rigo F, Bennett CF, Lutz C, Lagier-Tourenne C, Cleveland DW (2023) Mechanism of STMN2 cryptic splice-polyadenylation and its correction for TDP-43 proteinopathies. Science 379(6637):1140–1149. https://doi.org/10.1126/science.abq5622

4. Berry JD, Cudkowicz ME, Windebank AJ, Staff NP, Owegi M, Nicholson K, McKenna-Yasek D, Levy YS, Abramov N, Kaspi H, Mehra M, Aricha R, Gothelf Y, Brown RH (2019) NurOwn, phase 2, randomized, clinical trial in patients with ALS: Safety, clinical, and biomarker results. Neurolog 93(24):e2294–e2305. https://doi.org/10.1212/WNL.0000000000008620

5. Bogorad AM, Lin KY, Marintchev A (2018) eIF2B mechanisms of action and regulation: a thermodynamic view. Biochemistry 57(9):1426–1435. https://doi.org/10.1021/acs.biochem.7b00957
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