Cerebrospinal Fluid from Patients After Craniotomy with the Appearance of Interleukin-6 Storm Can Activate Microglia to Damage the Hypothalamic Neurons in Mice

Author:

Huang Haorun,Liao Xixian,Zhang An,Qiu Binghui,Mei Fen,Liu Fan,Zeng Kai,Yang Chunen,Ma Haidie,Ding Wenjie,Qi Songtao,Bao YunORCID

Funder

Province natural science fund of Guangdong

Medical Scientific Research Foundation of Guangdong Province of China

Clinical Research Program of Nafang Hospital, Southern Medical University

Clinical Research Startup Program of Southern Medical University by High-level University Construction Funding of Guangdong Provincial Department of Education

President Foundation of Nanfang Hospital, Southern Medical University

Publisher

Springer Science and Business Media LLC

Subject

Neuroscience (miscellaneous),Cellular and Molecular Neuroscience,Neurology

Reference61 articles.

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2. Zhou D, Wei D, Xing W, Li T, Huang Y (2021) Effects of craniotomy clipping and interventional embolization on treatment efficacy, cognitive function and recovery of patients complicated with subarachnoid hemorrhage. Am J Transl Res 13(5):5117–5126

3. Lisman J, Buzsáki G, Eichenbaum H, Nadel L, Ranganath C, Redish AD (2017) Viewpoints: how the hippocampus contributes to memory, navigation and cognition. Nat Neurosci 20(11):1434–1447

4. Evered LA, Chan MTV, Han R, Chu MHM, Cheng BP, Scott DA et al (2021) Anaesthetic depth and delirium after major surgery: a randomised clinical trial. Br J Anaesth 127(5):704–712

5. Hirano T, Taga T, Nakano N, Yasukawa K, Kashiwamura S, Shimizu K, et al (1985) Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2). Proc Natl Acad Sci U S A 82(16):5490-5494

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