Protective role of microRNA-23a/b-3p inhibition against osteoarthritis through Gremlin1-depenent activation of TGF-β/smad signaling in chondrocytesa
Author:
Funder
National Key R&D Program of China
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology,Immunology
Link
https://link.springer.com/content/pdf/10.1007/s10787-022-00923-1.pdf
Reference37 articles.
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2. Arellano RD, Aguilar LS, Arguello R, Hernadez F, Gonzalez FF, Moran J (2017) Cartilage oligomeric matrix protein levels in synovial fluid in patients with primary knee osteoarthritis and healthy controls: a preliminary comparative analysis with serum cartilage oligomeric matrix protein. Arch Rheumatol 32:189–196. https://doi.org/10.5606/ArchRheumatol.2017.6220
3. Bijlsma JW, Berenbaum F, Lafeber FP (2011) Osteoarthritis: an update with relevance for clinical practice. Lancet 377:2115–2126. https://doi.org/10.1016/S0140-6736(11)60243-2
4. Cao M, Seike M, Soeno C, Mizutani H, Kitamura K, Minegishi Y, Noro R, Yoshimura A, Cai L, Gemma A (2012) MiR-23a regulates TGF-beta-induced epithelial-mesenchymal transition by targeting E-cadherin in lung cancer cells. Int J Oncol 41:869–875. https://doi.org/10.3892/ijo.2012.1535
5. Chen M, Huang L, Zhang W, Shi J, Lin X, Lv Z, Zhang W, Liang R, Jiang S (2016) MiR-23b controls TGF-beta1 induced airway smooth muscle cell proliferation via TGFbetaR2/p-Smad3 signals. Mol Immunol 70:84–93. https://doi.org/10.1016/j.molimm.2015.12.012
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