Naringin regulates endoplasmic reticulum stress and mitophagy through the ATF3/PINK1 signaling axis to alleviate pulmonary fibrosis
Author:
Funder
Qingdao Scientific Plan of Medicine
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00210-023-02390-z.pdf
Reference54 articles.
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2. Andugulapati SB, Gourishetti K, Tirunavalli SK, Shaikh TB, Sistla R (2020) Biochanin-A ameliorates pulmonary fibrosis by suppressing the TGF-β mediated EMT, myofibroblasts differentiation and collagen deposition in in vitro and in vivo systems. Phytomedicine 78:153298. https://doi.org/10.1016/j.phymed.2020.153298
3. Bhatia D, Chung KP, Nakahira K, Patino E, Rice MC, Torres LK, Muthukumar T, Choi AM, Akchurin OM, Choi ME (2019) Mitophagy-dependent macrophage reprogramming protects against kidney fibrosis. JCI Insight 4:e132826. https://doi.org/10.1172/jci.insight.132826
4. Biczo G, Vegh ET, Shalbueva N, Mareninova OA, Elperin J, Lotshaw E, Gretler S, Lugea A, Malla SR, Dawson D, Ruchala P, Whitelegge J, French SW, Wen L, Husain SZ, Gorelick FS, Hegyi P, Rakonczay Z Jr, Gukovsky I, Gukovskaya AS (2018) Mitochondrial dysfunction, through impaired autophagy, leads to endoplasmic reticulum stress, deregulated lipid metabolism, and pancreatitis in animal models. Gastroenterology 154:689–703. https://doi.org/10.1053/j.gastro.2017.10.012
5. Borok Z, Horie M, Flodby P, Wang H, Liu Y, Ganesh S, Firth AL, Minoo P, Li C, Beers MF, Lee AS, Zhou B (2020) Grp78 Loss in epithelial progenitors reveals an age-linked role for endoplasmic reticulum stress in pulmonary fibrosis. Am J Respir Crit Care Med 201:198–211. https://doi.org/10.1164/rccm.201902-0451OC
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