The presymptomatic phase of amyotrophic lateral sclerosis: are we merely scratching the surface?

Author:

Chipika Rangariroyashe H.,Siah We Fong,McKenna Mary Clare,Li Hi Shing Stacey,Hardiman Orla,Bede PeterORCID

Funder

Health Research Board Ireland

Spastic Paraplegia Foundation, Inc.

Publisher

Springer Science and Business Media LLC

Subject

Neurology (clinical),Neurology

Reference136 articles.

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2. Mueller C, Berry JD, McKenna-Yasek DM, Gernoux G, Owegi MA, Pothier LM, Douthwright CL, Gelevski D, Luppino SD, Blackwood M, Wightman NS, Oakley DH, Frosch MP, Flotte TR, Cudkowicz ME, Brown RH Jr (2020) SOD1 Suppression with adeno-associated virus and microrna in familial ALS. The N Engl J Med 383:151–158

3. Omer T, Finegan E, Hutchinson S, Doherty M, Vajda A, McLaughlin RL, Pender N, Hardiman O, Bede P (2017) Neuroimaging patterns along the ALS-FTD spectrum: a multiparametric imaging study. Amyotroph Lateral Scler Front Degener 18:611–623

4. Burke T, Pinto-Grau M, Lonergan K, Bede P, O’Sullivan M, Heverin M, Vajda A, McLaughlin RL, Pender N, Hardiman O (2017) A Cross-sectional population-based investigation into behavioral change in amyotrophic lateral sclerosis: subphenotypes, staging, cognitive predictors, and survival. Ann Clini Transl Neurol 4:305–317

5. Finegan E, Chipika RH, Shing SLH, Hardiman O, Bede P (2019) Primary lateral sclerosis: a distinct entity or part of the ALS spectrum? Amyotroph Lateral Scler Front Degener 20:133–145

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