Prognostic Value of the Ratio of Hemoglobin to Red Blood Cell Distribution Width in Patients with Out-of-Hospital Cardiac Arrest: A Retrospective Study

Author:

Wang Hong,Luo Yao,Zhang Tangjuan,Lv Qing,Yang Liu,Jia Xinya,Zhou Yan,Li Renjie,Zhu Xingqiang,Lei Ruyi,Lan Chao

Abstract

Abstract Background The ratio of hemoglobin to red blood cell distribution width (HRR) can reflect the degree of oxidative stress and systemic inflammatory response in the body, and is a potential indicator to predict the prognosis of patients with cardiac arrest (CA). Methods We retrospectively analyzed 126 patients successfully resuscitated after out-of-hospital cardiac arrest. Patients were grouped according to their survival status at discharge: 35 survived and 91 died. Binary logistic regression was used to analyze the independent factors affecting the prognosis of patients after cardiopulmonary resuscitation (CPR). A receiver operating characteristic (ROC) curve was used to analyze the predictive value of each independent factor for the prognosis of patients after CPR. Results The HRR in death group was lower than that in the survival group (P < 0.05), which was closely related to the prognosis of patients after CPR. The ROC curve showed that HRR < 8.555 (AUC = 0.733, sensitivity 87.5%, specificity 40.7%, P < 0.001) indicated poor prognosis after CPR. Conclusions The HRR is an independent risk factor for the prognosis in patients who underwent CPR after out-of-hospital cardiac arrest. After successful resuscitation, HRR lower than 8.555 indicates poor prognosis.

Funder

National Natural Science Foundation of China Grant

the Medical Scientific and Technology Project of Henan Province Grant

the National Key Research and Development Program of China

the Henan Province Medical Science and technology research key project

Publisher

Springer Science and Business Media LLC

Reference35 articles.

1. Nolan J, Soar J, Zideman D, Biarent D, Bossaert L, Deakin C, et al. European Resuscitation Council Guidelines for Resuscitation 2010 Section 1. Executive summary. Resuscitation. 2010;81(10):1219–76. https://doi.org/10.1016/j.resuscitation.2010.08.021.

2. Myat A, Song K, Rea T. Out-of-hospital cardiac arrest: current concepts. Lancet (London, England). 2018;391(10124):970–9. https://doi.org/10.1016/s0140-6736(18)30472-0.

3. Panchal A, Bartos J, Cabañas J, Donnino M, Drennan I, Hirsch K, et al. Part 3: adult basic and advanced life support: 2020 american heart association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2020;142:S366-468. https://doi.org/10.1161/cir.0000000000000916.

4. Shao F, Li C, Liang L, Li D, Ma S. Outcome of out-of-hospital cardiac arrests in Beijing, China. Resuscitation. 2014;85(11):1411–7. https://doi.org/10.1016/j.resuscitation.2014.08.008.

5. Nolan J, Neumar R, Adrie C, Aibiki M, Berg R, Böttiger B, et al. Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A Scientific Statement from the International Liaison Committee on Resuscitation; the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; the Council on Stroke. Resuscitation. 2008;79(3):350–79. https://doi.org/10.1016/j.resuscitation.2008.09.017.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3