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Inhibitors of growth factor receptors, signaling pathways and angiogenesis as therapeutic molecular agents

  • Published:2006-06 Issue:2 Volume:25 Page:243-252
  • ISSN:0167-7659
  • Container-title:Cancer and Metastasis Reviews
  • language:en
  • Short-container-title:Cancer Metastasis Rev

Author:

Holash Jocelyn,Thurston Gavin,Rudge John S.,Yancopoulos George D.,Adjei Alex A.,Bergers Gabriele,Pytowski Bronislaw,Pegram Mark,Gordon Michael S.

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference75 articles.

1. Adjei AA, Rowinsky EK: Novel anticancer agents in clinical development. Cancer Biol Ther 2(4 Suppl 1): S5–15, 2003

2. Chen EX, Siu LL: Development of molecular targeted anticancer agents: Successes, failures and future directions. Curr Pharm Des 11(2): 265–272, 2005

3. Lyons JF, Wilhelm S, Hibner B, Bollag G: Discovery of a novel Raf kinase inhibitor. Endocr Relat Cancer 8(3): 219–225, 2001

4. Strumberg D, Schuehly U, Moeller J, Hedley D, Hilger R, Stellberg W, Richly H, Heinig R, Ahr G, Wensing G, Kuhlmann J, Schuelen ME, Seeber S: West German Cancer Center/University of Essen, Essen, Germany; Bayer AG, Wuppertal, Germany; Princess Margaret Hospital, University of Toronto, Toronto, Canada.: Phase I clinical, pharmacokinetic, and pharmacodynamic study of the Raf kinase inhibitor BAY 43-9006 in patients with locally advanced or metastatic cancer. Proc Am Soc Clin Oncol 20(abstr 330.), 2001

5. Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, Hawes R, Hughes J, Kosmidou V, Menzies A, Mould C, Parker A, Stevens C, Watt S, Hooper S, Wilson R, Jayatilake H, Gusterson BA, Cooper C, Shipley J, Hargrave D, Pritchard-Jones K, Maitland N, Chenevix-Trench G, Riggins GJ, Bigner DD, Palmieri G, Cossu A, Flanagan A, Nicholson A, Ho JW, Leung SY, Yuen ST, Weber BL, Seigler HF, Darrow TL, Paterson H, Marais R, Marshall CJ, Wooster R, Stratton MR, Futreal PA: Mutations of the BRAF gene in human cancer. Nature 417(6892): 949–954, 2002

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