Continuous Electroencephalogram (cEEG) Findings and Neurodevelopmental Outcomes in Neonates with Congenital Heart Disease (CHD) at 12–24 Months of Age
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Published:2024-05-31
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Volume:
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ISSN:0162-3257
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Container-title:Journal of Autism and Developmental Disorders
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language:en
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Short-container-title:J Autism Dev Disord
Author:
Padiyar SwethaORCID, Friedman Neil, Pestana-Knight Elia, Franic Linda, Worley Sarah, Aly Hany
Abstract
Abstract
Objective
This study aims to assess the role of continuous EEG (cEEG) background patterns and duration of cross-clamp time and cardiopulmonary bypass (CPB) in children with congenital heart disease (CHD) undergoing cardiac surgery and its correlation with abnormal neurodevelopmental outcomes at 12–24 months on Bayley Scales of Infant and Toddler Development (BSID-III).
Methods
This retrospective cohort study included infants with CHD and cEEG monitoring, who underwent surgery by 44 weeks gestational age.
Results
34 patients were included, who were operated at median age − 7 days. Longer duration of cross- camp time was associated with poor language composite scores (LCS) (p value = 0.036). A significant association existed between severity of encephalopathy in 24-hour post-operative period and poor LCS (p value = 0.026).
Conclusion
Majority of neonates with CHD have below average cognitive, language and motor composite scores on BSID-III. Longer duration of cross-clamp time and severity of encephalopathy during 24-hour post-operative EEG monitoring are associated with poor LCS.
Funder
Wake Forest University
Publisher
Springer Science and Business Media LLC
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