Abstract
AbstractAutism spectrum disorder (ASD) is a developmental disorder characterised by deficits in social interactions and communication, with stereotypical and repetitive behaviours. Recent evidence suggests that maternal immune dysregulation may predispose offspring to ASD. Independent samples t-tests revealed downregulation of IL-17A concentrations in cases, when compared to controls, at both 15 weeks (p = 0.02), and 20 weeks (p = 0.02), which persisted at 20 weeks following adjustment for confounding variables. This adds to the growing body of evidence that maternal immune regulation may play a role in foetal neurodevelopment.
Funder
Irish Research Council for Science, Engineering and Technology
National Children's Research Centre
Health Research Board
Science Foundation Ireland
Health Research Council of New Zealand
University College Cork
Publisher
Springer Science and Business Media LLC
Subject
Developmental and Educational Psychology
Cited by
9 articles.
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