Efficacy and safety of remimazolam versus propofol for general anesthesia: a multicenter, single-blind, randomized, parallel-group, phase IIb/III trial

Author:

Doi MatsuyukiORCID,Morita Kiyoshi,Takeda Junzo,Sakamoto Atsuhiro,Yamakage Michiaki,Suzuki Toshiyasu

Publisher

Springer Science and Business Media LLC

Subject

Anesthesiology and Pain Medicine

Reference23 articles.

1. Chitilian HV, Eckenhoff RG. Anesthetic drug development: novel drugs and new approaches. Surg Neurol Int. 2013;4(Suppl1):S2–S10.

2. Scott RP, Saunders DA. Propofol: clinical strategies for preventing the pain of injection. Anaesthesia. 1988;43:492–4.

3. Sneyd JR, Rigby-Jones AE. New drugs and technologies, intravenous anaesthesia is on the move (again). Br J Anaesth. 2010;105:246–54.

4. Tuk B, van Oostenbruggen MF. Characterization of the pharmacodynamic interaction between parent drug and active metabolite in vivo: midazolam and alpha-OH-midazolam. J Pharmacol Exp Ther. 1999;289:1067–74.

5. Saari TI, Uusi-Oukari M. Enhancement of GABAergic activity: neuropharmacological effects of benzodiazepines and therapeutic use in anesthesiology. Pharmacol Rev. 2011;63:243–67.

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