Pharmacophore modeling, docking and molecular dynamics simulation for identification of novel human protein kinase C beta (PKCβ) inhibitors
Author:
Funder
National Research Foundation of Ukraine
Publisher
Springer Science and Business Media LLC
Subject
Physical and Theoretical Chemistry,Condensed Matter Physics
Link
https://link.springer.com/content/pdf/10.1007/s11224-022-02075-y.pdf
Reference60 articles.
1. Newton AC (1995) Protein kinase C: structure, function, and regulation. J Biol Chem 270:28495–28498. https://doi.org/10.1074/jbc.270.48.28495
2. Black AR, Black JD (2013) Protein kinase C signaling and cell cycle regulation. Front Immunol 3:423. https://doi.org/10.3389/fimmu.2012.00423
3. Kim H, Zamel R, Bai X-H, Liu M (2013) PKC activation induces inflammatory response and cell death in human bronchial epithelial cells. PLoS ONE 8:e64182. https://doi.org/10.1371/journal.pone.0064182
4. Freeley M, Lelleher D, Long A (2011) Regulation of protein kinase C function by phosphorylation on conserved and non-conserved sites. Cell Signal 23:753–762. https://doi.org/10.1016/j.cellsig.2010.10.013
5. Churchill E, Budas G, Vallentin A, Koyanagi T, Mochly-Rosen D (2008) PKC isozymes in chronic cardiac disease: possible therapeutic targets? Annu Rev Pharmacol Toxicol 48:569–599. https://doi.org/10.1146/annurev.pharmtox.48.121806.154902
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Novel Pyrimidin-4-yl-3-amino-pyrrolo[3,4-c]pyrazoles as Protein Kinase C Inhibitors for Treating Diseases;Current Medicinal Chemistry;2024-03
2. Identification of Active Compounds against Melanoma Growth by Virtual Screening for Non-Classical Human DHFR Inhibitors;International Journal of Molecular Sciences;2022-11-11
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3