Characterization of a novel thermophilic beta-glucosidase from Thermotoga sp. and its application in the transformation of notoginsenoside R1
Author:
Funder
Jilin Scientific and Technological Development Program
Publisher
Springer Science and Business Media LLC
Subject
Agricultural and Biological Sciences (miscellaneous),Environmental Science (miscellaneous),Biotechnology
Link
https://link.springer.com/content/pdf/10.1007/s13205-022-03352-7.pdf
Reference43 articles.
1. Bi YF, Wang XZ, Jiang S et al (2019) Enzymatic transformation ofginsenosides Re, Rg1, and Rf to ginsenosides Rg2 and aglycon PPT using β-glucosidase from Thermotoga neapolitana. Biotechnol Lett 41(4–5):613–623. https://doi.org/10.1007/s10529-019-02665-7
2. Cui CH, Kim SC, Im WT (2013a) Characterization of the ginsenoside-transforming recombina-nt beta-glucosidase from Actinosynnema mirum and bioconversion of major ginsenosides into minor ginsenosides. Appl Microbiol Biotechnol 97:649–659. https://doi.org/10.1007/s00253-012-4324-5
3. Cui CH, Liu QM, Kim JK et al (2013b) Identification and characterization of a Mucilaginiba-cter sp. strain QM49 beta-glucosidase and its use in the production of the pharmaceutic-ally active minor ginsenosides (S)-Rh1 and (S)-Rg2. Appl Environ Microbiol 79:5788–5798. https://doi.org/10.1128/AEM.01150-13
4. Drula E, Garron ML, Dogan S et al (2022) The carbohydrate-active enzyme database: functions and literature. Nucleic Acids Res 50(D1):D571–D577. https://doi.org/10.1093/nar/gkab1045
5. Fan C, Chen Q, Ren J et al (2020) Notoginsenoside R1 suppresses inflammatory signaling a-nd rescues renal ischemia-reperfusion injury in experimental rats. Med Sci Monit 26:1234–1010. https://doi.org/10.12659/msm.920442
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1. Enhancing the inhibition of cell proliferation and induction of apoptosis in H22 hepatoma cells through biotransformation of notoginsenoside R1 by Lactiplantibacillus plantarum S165 into 20(S/R)-notoginsenoside R2;RSC Advances;2023
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