LC–MS Approach to Decipher a Light Chain Chromatographic Peak Splitting of a Monoclonal Antibody
Author:
Funder
Merck Sharp and Dohme
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology
Link
https://link.springer.com/content/pdf/10.1007/s11095-023-03631-9.pdf
Reference42 articles.
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2. Kaplon H, et al. Antibodies to watch in 2022. MAbs. 2022;14(1):2014296.
3. Chiu ML, et al. Antibody structure and function: the basis for engineering therapeutics. Antibodies (Basel). 2019;8(4):55.
4. Goetze AM, Schenauer MR, Flynn GC. Assessing monoclonal antibody product quality attribute criticality through clinical studies. MAbs. 2010;2(5):500–7.
5. Gupta S, et al. Oxidation and deamidation of monoclonal antibody products: potential impact on stability, biological activity, and efficacy. J Pharm Sci. 2022;111(4):903–18.
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