Evaluation of antibacterial, antioxidant, cytotoxic, and acetylcholinesterase inhibition activities of novel [1,4] benzoxazepines fused to heterocyclic systems with a molecular modeling study
Author:
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics
Link
https://link.springer.com/content/pdf/10.1007/s00044-022-02999-4.pdf
Reference68 articles.
1. Stanisheva D, Gerova M, Petrov O. Synthesis of a new polycyclic heterocyclic ring system. part III. Benzo[b]imidazo[1,5-d][1,4]oxazepine-1,4(2H,5H)-diones. Heterocycl Commun. 2017;23:23–7. https://doi.org/10.1515/hc-2016-0236.
2. Tóth L, Fu Y, Zhang HY, Mándi A, Kövér KE, Illyés TZ, et al. Preparation of neuroprotective condensed 1,4-benzoxazepines by regio- and diastereoselective domino Knoevenagel-[1,5]-hydride shift cyclization reaction. Beilstein J Org Chem. 2014;10:2594–602. https://doi.org/10.3762/bjoc.10.272.
3. Grunewald GL, Dahanukar VH, Ching P, Criscione KR. Effect of ring size or an additional heteroatom on the potency and selectivity of bicyclic benzylamine-type inhibitors of phenylethanolamine N-methyltransferase. J Med Chem. 1996;39:3539–46. https://doi.org/10.1021/jm9508292.
4. Ashok D, Radhika G, Ananda Rao B, Sarasija M, Jayashree A, Sadanandam P. Synthesis of benzoxazepine derivatives from pyrazole-chalcone via a simple and convenient protocol using basic alumina as solid support. Chil Chem Soc. 2018;63:3983–7. https://doi.org/10.4067/s0717-97072018000203983.
5. Bright SA, Campiani G, Deininger MW, Lawler M, Williams DC, Zisterer DM. Sequential treatment with flavopiridol synergistically enhances pyrrolo-1,5-benzoxazepine-induced apoptosis in human chronic myeloid leukaemia cells including those resistant to imatinib treatment. Biochem Pharmacol. 2010;80:31–8. https://doi.org/10.1016/j.bcp.2010.02.019.
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