FOXO1 promotes endothelial cell elongation and angiogenesis by up-regulating the phosphorylation of myosin light chain 2
Author:
Funder
Japan Society for the Promotion of Science
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Clinical Biochemistry,Physiology
Link
https://link.springer.com/content/pdf/10.1007/s10456-023-09884-7.pdf
Reference65 articles.
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2. Salih DA, Brunet A (2008) FoxO transcription factors in the maintenance of cellular homeostasis during aging. Curr Opin Cell Biol 20:126–136. https://doi.org/10.1016/j.ceb.2008.02.005
3. Kim YH, Choi J, Yang MJ et al (2019) A MST1–FOXO1 cascade establishes endothelial tip cell polarity and facilitates sprouting angiogenesis. Nat Commun 10:838. https://doi.org/10.1038/s41467-019-08773-2
4. Tsuchiya K, Tanaka J, Shuiqing Y et al (2012) FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis. Cell Metab 15:372–381. https://doi.org/10.1016/j.cmet.2012.01.018
5. Benchoula K, Arya A, Parhar IS, Hwa WE (2021) FoxO1 signaling as a therapeutic target for type 2 diabetes and obesity. Eur J Pharmacol 891:173758. https://doi.org/10.1016/j.ejphar.2020.173758
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