Utility of physiologically based pharmacokinetic (PBPK) modeling in oncology drug development and its accuracy: a systematic review
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology,General Medicine
Link
http://link.springer.com/article/10.1007/s00228-018-2513-6/fulltext.html
Reference75 articles.
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3. Rowland M, Lesko LJ, Rostami-Hodjegan A (2015) Physiologically based pharmacokinetics is impacting drug development and regulatory decision making. CPT Pharmacometrics Syst Pharmacol. https://doi.org/10.1002/psp4.52
4. Theil FP, Guentert TW, Haddad S, Poulin P (2003) Utility of physiologically based pharmacokinetic models to drug development and rational drug discovery candidate selection. Toxicol Lett. https://doi.org/10.1016/S0378-4274(02)00374-0
5. Poggesi I, Snoeys J, Van Peer A (2014) The successes and failures of physiologically based pharmacokinetic modeling: there is room for improvement. Expert Opin Drug Metab Toxicol. https://doi.org/10.1517/17425255.2014.888058
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