Effect of pregnane X receptor and cytochrome P450 oxidoreductase gene polymorphisms on trough concentrations of rivaroxaban and edoxaban in patients with nonvalvular atrial fibrillation
Author:
Funder
The Policy-Based Medical Services Foundation of Japan
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00228-023-03483-7.pdf
Reference10 articles.
1. Nakagawa J, Kinjo T, Aiuchi N, Ueno K, Tomita H, Niioka T (2023) Impacts of pregnane X receptor and cytochrome P450 oxidoreductase gene polymorphisms on trough concentrations of apixaban in patients with non-valvular atrial fibrillation. Eur J Clin Pharmacol 79:127–135. https://doi.org/10.1007/s00228-022-03424-w
2. Foerster KI, Hermann S, Mikus G, Haefeli WE (2020) Drug-drug interactions with direct oral anticoagulants. Clin Pharmacokinet 59:967–980. https://doi.org/10.1007/s40262-020-00879-x
3. Oneda B, Crettol S, JaquenoudSirot E, Bochud M, Ansermot N, Eap CB (2009) The P450 oxidoreductase genotype is associated with CYP3A activity in vivo as measured by the midazolam phenotyping test. Pharmacogenet Genomics 19:877–883. https://doi.org/10.1097/FPC.0b013e32833225e7
4. Agrawal V, Huang N, Miller WL (2008) Pharmacogenetics of P450 oxidoreductase: effect of sequence variants on activities of CYP1A2 and CYP2C19. Pharmacogenet Genomics 18:569–576. https://doi.org/10.1097/FPC.0b013e32830054ac
5. Mbatchi LC, Brouillet JP, Evrard A (2018) Genetic variations of the xenoreceptors NR1I2 and NR1I3 and their effect on drug disposition and response variability. Pharmacogenomics 19:61–77. https://doi.org/10.2217/pgs-2017-0121
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