Abstract
AbstractFive undescribed alkaloids were isolated from the seeds of Cephalotaxus oliveri along with 27 known ones. The new structures were elucidated based on spectroscopic data including 1D and 2D NMR, MS and calculated ECD spectra. Among them, (+)-acetylcephalofortine C was an enantiomeric Cephalotaxine alkaloids. The performed bioassay revealed that those alkaloids were not cytotoxic against cancer cells and had no neuroprotective properties in the HEI-OC-1 cells model.
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Plant Science,Pharmacology,Toxicology,Biochemistry,Food Science,Analytical Chemistry
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