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Tumor-derived VEGF-C, but not VEGF-D, promotes sentinel lymph node lymphangiogenesis prior to metastasis in breast cancer patients

  • Published:2012-05-06 Issue:4 Volume:29 Page:2594-2600
  • ISSN:1357-0560
  • Container-title:Medical Oncology
  • language:en
  • Short-container-title:Med Oncol

Author:

Zhao Ying-Chun,Ni Xiao-Jian,Wang Ming-Hai,Zha Xiao-Ming,Zhao Yi,Wang Shui

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,Hematology,General Medicine

Reference45 articles.

1. Tuttle TM. Technical advances in sentinel lymph node biopsy for breast cancer. Am Surg. 2004;70:407–13.

2. Pepper MS. Lymphangiogenesis and tumor metastasis: myth or reality? Clin Cancer Res. 2001;7:462–8.

3. Skobe M, Hawighorst T, Jackson DG, Prevo R, Janes L, Velasco P, et al. Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis. Nat Med. 2001;7:192–8.

4. He Y, Karpanen T, Alitalo K. Role of lymphangiogenic factors in tumor metastasis. Biochim Biophys Acta. 2004;1654:3–12.

5. Oliver G, Detmar M. The rediscovery of the lymphatic system: old and new insights into the development and biological function of the lymphatic vasculature. Genes Dev. 2002;16:773–83.

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