Machine learning driven drug repurposing strategy for identification of potential RET inhibitors against non-small cell lung cancer
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology,Hematology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s12032-022-01924-4.pdf
Reference55 articles.
1. Wang M, Naganna N, Sintim HO. Identification of nicotinamide aminonaphthyridine compounds as potent RET kinase inhibitors and antitumor activities against RET rearranged lung adenocarcinoma. Bioorg Chem. 2019;90: 103052. https://doi.org/10.1016/j.bioorg.2019.103052.
2. Mendoza L. Clinical development of RET inhibitors in RET-rearranged non-small cell lung cancer: update. Oncol Rev. 2018;12(2):352. https://doi.org/10.4081/oncol.2018.352.
3. Ferrara R, Auger N, Auclin E, Besse B. Clinical and translational implications of RET rearrangements in non-small cell lung cancer. J Thorac Oncol. 2018;13(1):27–45. https://doi.org/10.1016/j.jtho.2017.10.021.
4. Subbiah V, Gainor JF, Rahal R, Brubaker JD, Kim JL, Maynard M, Hu W, Cao Q, Sheets MP, Wilson D, Wilson KJ, DiPietro L, Fleming P, Palmer M, Hu MI, Wirth L, Brose MS, Ou SI, Taylor M, Garralda E, Miller S, Wolf B, Lengauer C, Guzi T, Evans EK. Precision targeted therapy with BLU-667 for RET-driven cancers. Cancer Discov. 2018;8(7):836–49. https://doi.org/10.1158/2159-8290.CD-18-0338.
5. Ramesh P, Veerappapillai S. Designing novel compounds for the treatment and management of RET-positive non-small cell lung cancer-fragment based drug design strategy. Molecules. 2022;27(5):1590. https://doi.org/10.3390/molecules27051590.
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