Synthesis of Pyrazoline derivatives, condensation of β-dicarbonyl compounds with isoniazid (INH), and their biological evaluation as multitarget anti-Alzheimer’ disease agents

Author:

Kanwal MadihaORCID,Sarwar Sadia,Nadeem Humaira,Zafar Rehman,Rahman Khondaker Miraz

Publisher

Springer Science and Business Media LLC

Subject

Materials Chemistry,Industrial and Manufacturing Engineering,General Chemical Engineering,Biochemistry,General Chemistry

Reference38 articles.

1. Acharya BN et al (2010) Synthesis and antimalarial evaluation of 1, 3, 5-trisubstituted pyrazolines. Eur j Med Chem 45(2):430–438

2. Adeowo FY et al (2022) Pharmacophore Mapping of the Crucial Mediators of Acetylcholinesterase and Butyrylcholinesterase Dual Inhibition in Alzheimer’s Disease 26(5):2761–2774

3. Ali, M.A., M. Shaharyar, and A.A.J.E.j.o.m.c. Siddiqui, Synthesis, structural activity relationship and anti-tubercular activity of novel pyrazoline derivatives. 2007. 42(2): p. 268–275.

4. Altıntop, M.D., et al., A novel series of thiazolyl–pyrazoline derivatives: Synthesis and evaluation of antifungal activity, cytotoxicity and genotoxicity. 2015. 92: p. 342–352.

5. Amin KM et al (2021) Design and Synthesis of Novel Coumarin Derivatives as Potential Acetylcholinesterase Inhibitors for Alzheimer’s Disease 110:104792

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