Myelotoxicity after high-dose methotrexate in childhood acute leukemia is influenced by 6-mercaptopurine dosing but not by intermediate thiopurine methyltransferase activity-Reference-Cited by-同舟云学术

Myelotoxicity after high-dose methotrexate in childhood acute leukemia is influenced by 6-mercaptopurine dosing but not by intermediate thiopurine methyltransferase activity

Published:2014-10-28 Issue:1 Volume:75 Page:59-66
ISSN:0344-5704
Container-title:Cancer Chemotherapy and Pharmacology
language:en
Short-container-title:Cancer Chemother Pharmacol

Author:

Levinsen Mette,Rosthøj Susanne,Nygaard Ulrikka,Heldrup Jesper,Harila-Saari Arja,Jonsson Olafur G.,Bechensteen Anne Grete,Abrahamsson Jonas,Lausen Birgitte,Frandsen Thomas L.,Weinshilboum Richard M.,Schmiegelow Kjeld

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Link

http://link.springer.com/content/pdf/10.1007/s00280-014-2613-7.pdf

Reference45 articles.

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2. Clarke M, Gaynon P, Hann I, Harrison G, Masera G, Peto R, Richards S (2003) CNS-directed therapy for childhood acute lymphoblastic leukemia: Childhood ALL Collaborative Group overview of 43 randomized trials. J Clin Oncol 21:1798–1809

3. Pui CH, Thiel E (2009) Central nervous system disease in hematologic malignancies: historical perspective and practical applications. Semin Oncol 36:S2–S16

4. Nathan PC, Whitcomb T, Wolters PL, Steinberg SM, Balis FM, Brouwers P, Hunsberger S, Feusner J, Sather H, Miser J, Odom LF, Poplack D, Reaman G, Bleyer WA (2006) Very high-dose methotrexate (33.6 g/m2) as central nervous system preventive therapy for childhood acute lymphoblastic leukemia: results of National Cancer Institute/Children’s Cancer Group trials CCG-191P, CCG-134P and CCG-144P. Leuk Lymphoma 47:2488–2504

5. Pui CH, Evans WE (1998) Acute lymphoblastic leukemia. N Engl J Med 339:605–615

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