Selective Serotonin Reuptake Inhibitor (SSRI) Bleeding Risk: Considerations for the Consult-Liaison Psychiatrist-Reference-Cited by-同舟云学术

Selective Serotonin Reuptake Inhibitor (SSRI) Bleeding Risk: Considerations for the Consult-Liaison Psychiatrist

Published:2023-01-28 Issue:3 Volume:25 Page:113-124
ISSN:1523-3812
Container-title:Current Psychiatry Reports
language:en
Short-container-title:Curr Psychiatry Rep

Author:

McFarland Daniel,Merchant Dale,Khandai Abhisek,Mojtahedzadeh Mona,Ghosn Omar,Hirst Jeremy,Amonoo Hermioni,Chopra Depti,Niazi Shehzad,Brandstetter Jennifer,Gleason Andrew,Key Garrett,di Ciccone Barbara Lubrano

Publisher

Springer Science and Business Media LLC

Subject

Psychiatry and Mental health

Link

https://link.springer.com/content/pdf/10.1007/s11920-023-01411-1.pdf

Reference64 articles.

1. • Laporte S, Chapelle C, Caillet P, Beyens MN, Bellet F, Delavenne X, et al. Bleeding risk under selective serotonin reuptake inhibitor (SSRI) antidepressants: a meta-analysis of observational studies. Pharmacol Res. 2017;118:19–32. This meta-analysis demonstrates all-sites elevated risk of bleeding from SSRI antidepressant medications.

2. •• Andrade C, Sandarsh S, Chethan KB, Nagesh KS. Serotonin reuptake inhibitor antidepressants and abnormal bleeding: a review for clinicians and a reconsideration of mechanisms. J Clin Psychiatry. 2010;71(12):1565–75. Bleeding risk from SSRI antidepressants is highest for gastrointestinal types of bleeding which is roughly double from other sites of bleeding.

3. Anglin R, Yuan Y, Moayyedi P, Tse F, Armstrong D, Leontiadis GI. Risk of upper gastrointestinal bleeding with selective serotonin reuptake inhibitors with or without concurrent nonsteroidal anti-inflammatory use: a systematic review and meta-analysis. Am J Gastroenterol. 2014;109(6):811–9.

4. Nochaiwong S, Ruengorn C, Awiphan R, Chai-Adisaksopha C, Tantraworasin A, Phosuya C, et al. Use of serotonin reuptake inhibitor antidepressants and the risk of bleeding complications in patients on anticoagulant or antiplatelet agents: a systematic review and meta-analysis. Ann Med. 2022;54(1):80–97.

5. • Jiang HY, Chen HZ, Hu XJ, Yu ZH, Yang W, Deng M, et al. Use of selective serotonin reuptake inhibitors and risk of upper gastrointestinal bleeding: a systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2015;13(1):42-50.e3. The risk of upper GI bleeding may be mitigated by antiacid medication.

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