Clinical, immunologic, and genetic characteristics of RAG mutations in 15 Chinese patients with SCID and Omenn syndrome

Author:

Bai Xiaoming,Liu Jing,Zhang Zhiyong,Liu Chaohong,Zhang Yongjie,Tang Wenjing,Dai Rongxin,Wu Junfeng,Tang Xuemei,Zhang Yu,Ding Yuan,Jiang Liping,Zhao Xiaodong

Funder

National Natural Science Foundation of China (CN)

Public Welfare Scientific Research Project of China

Publisher

Springer Science and Business Media LLC

Subject

Immunology

Reference30 articles.

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2. Bogaert D, Van Schil K, Taghon T, Bordon V, Bonroy C, Dullaers M, et al. Persistent rotavirus diarrhea post-transplant in a novel JAK3-SCID patient after vaccination. Pediatr Allergy Immunol. 2015. doi: 10.1111/pai.12455 .

3. McBlane JF, van Gent DC, Ramsden DA, Romeo C, Cuomo CA, Gellert M, et al. Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps. Cell. 1995;83(3):387–95.

4. Oettinger MA, Schatz DG, Gorka C, Baltimore D. RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science. 1990;248(4962):1517–23.

5. van Gent DC, Ramsden DA, Gellert M. The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination. Cell. 1996;85(1):107–13.

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