The expression of mammalian target of rapamycin in Ishikawa and HEC-1A cells

Author:

Li Xiaomao,Xiao Lan,Yang Yuebo,Shen Huimin,Zeng Haitao,Wang Zehua

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Biomedical Engineering,Biomaterials,Biochemistry

Reference10 articles.

1. Janus A, Robak T, Smolewski P. The mammalian target of the rapamycin (mTOR) kinase pathway: its role in tumourigenesis and targeted anti-tumour therapy. Cell Mol Biol Lett, 2005,10:479–498

2. Xu G, Zhang W, Bertram P et al. Pharmacogenomic profiling of the PI3K/PTEN/AKT/mTOR pathway in common human tumor. Int J Oncol, 2004,24(4):901–908

3. Sahin F, Kannangai R, Adegbola O et al. mTOR and P70 S6 kinase expression in primary liver neoplasms. Clin Cancer Res, 2004,10:8421–8425

4. Ito D, Fujimoto K, Mori T et al. In vivo antitumor effect of the mTOR inhibitor CCI2779 and gemcitabine in xenograft models of human pancreatic cancer. Int J Cancer, 2006,118:2337–2343

5. Altomare D A, You H, Xiao G H et al. Human and mouse mesotheliomas exhibit elevated activity, which can be targeted pharmacologically to inhibit tumor cell growth. Oncogene, 2005,24(40):6080–6089

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