1. Gilbaldi M. Introduction to Pharmacokinetics.In:Gilbaldi M, ed.Biopharmaceutics and Clinical Pharmacokinetics4th Edition ed. Philadelphia:Lea &Febiger; 1991:113.
2. Takimoto CH, Lu ZL, Shang R, Liang MD, Larson LV, Cantilena LR, Grem JL, Allegra CJ, Diasio RB, Chu E. Severe neurotoxicity following 5-fluorouracil-based chemotherapy in a patient with dihydropyrimidine dehydrogenase deficiency.Clin Cancer Res.1996;2:477–481.
3. Chabner BA, Stoller RG, Hande K, Jacobs S, Young RC. Methotrexate disposition in humans: case studies in ovarian cancer and following high-dose infusion.Drug
Metab Rev.1978;8:107–17.
4. Ratain MJ. Therapeutic relevance of pharmacokinetics and pharmacodynamics.Sem
Oncol.1992;19:8–13.
5. Grem JL, Yee LK, Venzon DJ, Takimoto CH, Allegra CJ. Inter-and intraindividual variation in dihydropyrimidine dehydrogenase activity in peripheral blood mononuclear cells.Cancer Chemother Pharmacol.1997;40:117–25.