Prophylaktische Strahlentherapie bei asymptomatischen Hochrisiko-Knochenmetastasen
Author:
Funder
Herzzentrum Göttingen
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Radiology, Nuclear Medicine and imaging
Link
https://link.springer.com/content/pdf/10.1007/s00066-023-02195-2.pdf
Reference5 articles.
1. Gillespie EF, Yang JC, Mathis NJ, Marine CB, White C, Zhang Z, Barker CA, Kotecha R, McIntosh A, Vaynrub M, Bartelstein MK, Mitchell A, Guttmann DM, Yerramilli D, Higginson DS, Yamada YJ, Kohutek ZA, Powell SN, Tsai J, Yang JT (2023) Prophylactic radiation therapy versus standard of care for patients with high-risk asymptomatic bone metastases: a multicenter, randomized phase II clinical trial. J Clin Oncol. https://doi.org/10.1200/JCO.23.00753
2. Rosen LS, Gordon D, Tchekmedyian NS, Yanagihara R, Hirsh V, Krzakowski M, Pawlicki M, de Souza P, Zheng M, Urbanowitz G, Reitsma D, Seaman J (2004) Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: a randomized, Phase III, double-blind, placebo-controlled trial. Cancer 100:2613–2621. https://doi.org/10.1002/cncr.20308
3. Shulman RM, Meyer JE, Li T, Howell KJ (2019) External beam radiation therapy (EBRT) for asymptomatic bone metastases in patients with solid tumors reduces the risk of skeletal-related events (SREs). Ann Palliat Med 8:159–167. https://doi.org/10.21037/apm.2018.10.04
4. Rosen DB, Benjamin CD, Yang JC, Doyle C, Zhang Z, Barker CA, Vaynrub M, Yang TJ, Gillespie EF (2020) Early palliative radiation versus observation for high-risk asymptomatic or minimally symptomatic bone metastases: study protocol for a randomized controlled trial. BMC Cancer 20:1115. https://doi.org/10.1186/s12885-020-07591-w
5. Machado M, Cruz LS, Tannus G, Fonseca M (2009) Efficacy of clodronate, pamidronate, and zoledronate in reducing morbidity and mortality in cancer patients with bone metastasis: a meta-analysis of randomized clinical trials. Clin Ther 31:962–979. https://doi.org/10.1016/j.clinthera.2009.05.009
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