Blocking the PD-1 signal transduction by occupying the phosphorylated ITSM recognition site of SHP-2-Reference-Cited by-同舟云学术

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Blocking the PD-1 signal transduction by occupying the phosphorylated ITSM recognition site of SHP-2

Published:2024-08-29 Issue: Volume: Page:
ISSN:1674-7305
Container-title:Science China Life Sciences
language:en
Short-container-title:Sci. China Life Sci.

Author:

Li Wenjie,Mei Wenyi,Jiang Hewei,Wang Jie,Li Xiaoli,Quan Lina,Diao Yanyan,Ma Yanni,Fan Sisi,Xie Zhuwei,Gong Mengdie,Zhu Huan,Bi Dewen,Zhang Feng,Ma Lei,Zhang Jian,Gao Yufeng,Paschalidis Aris,Lin Honghuang,Liu Fangfang,Liu Kangdong,Ye Mingliang,Zhao Zhenjiang,Duan Yajun,Chen Zhuo,Xu Yufang,Xiao Weilie,Tao Shengce,Zhu Lili,Li Honglin

Publisher

Springer Science and Business Media LLC

Link

https://link.springer.com/content/pdf/10.1007/s11427-024-2706-2.pdf

Reference45 articles.

1. Akinleye, A., and Rasool, Z. (2019). Immune checkpoint inhibitors of PD-L1 as cancer therapeutics. J Hematol Oncol 12, 92–104.

2. Atanasov, A.G., Zotchev, S.B., Dirsch, V.M., and Supuran, C.T. (2021). Natural products in drug discovery: advances and opportunities. Nat Rev Drug Discov 20, 200–216.

3. Bagdanoff, J.T., Chen, Z., Acker, M., Chen, Y.N., Chan, H., Dore, M., Firestone, B., Fodor, M., Fortanet, J., Hentemann, M., et al. (2019). Optimization of fused bicyclic allosteric SHP2 inhibitors. J Med Chem 62, 1781–1792.

4. Boussiotis, V.A. (2016). Molecular and biochemical aspects of the PD-1 checkpoint pathway. N Engl J Med 375, 1767–1778.

5. Brahmer, J.R., Hammers, H., and Lipson, E.J. (2015). Nivolumab: targeting PD-1 to bolster antitumor immunity. Future Oncol 11, 1307–1326.

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